Table 1.

Model parameters, estimates, and lower and upper limits

Parameter	Definition	Lower Limit	Estimate	Upper Limit
α	Vaccine era CRS incidence (cases per 10,000 live births)a, b	-	0.00	-
β	Pre-vaccine era CRS incidence (cases per 10,000 live births)c	2.0	4.0	15
γ	Live births per year (rounded to the nearest 1000)b, d	-	4,150,000	-
δ	Percentage of CRS cases presenting with an ASD	3.0%	7.4%	10.0%

All data are from the United States unless otherwise specified in Methods.

^a Averaged over 2001-2008.

^b Parameter was not varied in sensitivity analyses (no lower and upper limit given).

^c Lower limit, upper limit, and estimate correspond to endemic, epidemic, and overall CRS incidence, respectively.

^d Averaged over 2001-2009.