Table 1.
Comparison of properties of reconstructed metabolic network for selected pathogens
| Model | N.A.* | AbyMBEL891 | iNJ661 | iRR1083 | iMO1056 | iKF1028 |
|---|---|---|---|---|---|---|
| Genome size | 2.8 Mb | 3.93 Mb | 4.4 Mb | 4.8 Mb | 6.3 Mb | 8.1 Mb |
| Included genes | 758 | 650 | 661 | 1,083 | 1,056 | 1,028 |
| Total reactions | 1,497 | 891 | 939 | 1,087 | 883 | 859 |
| Gene-associated reactions (% of total reactions) | 1,278 | 713 (80%) | 723 (77%) | 1,018 (93.7%) | 839 (95%) | 832 (96.9%) |
| Non-gene-associated reactions | 219 | 46 | 216 | 69 | 44 | 27 |
| Transport reactions | 146 | 130 | 93 | 230 | 133 | 102 |
| Metabolites | 1,431 | 778 | 828 | 744 | 760 | 834 |
Properties of metabolic reconstruction of B. cenocepacia J2315 (iKF1028) were compared with other published metabolic reconstructions of pathogenic microbes, S. aureus N315 (2009) [18] (which is the improvement of the N315 reconstruction by Becker and Palsson 2005 [19], and Heinermann et al. 2005 [20]), A. baumannii AYE (AbyMBEL891) (2010) [21], M. tuberculosis H37Rv (iNJ661) (2007) [22], S. typhimurium LT2 (iRR1083) (2009) [23], and P. aeruginosa PAO1 (iMO1056) (2008) [24]. *: Not available for the reconstruction of S. aureus N315.