Table 6.
Non-parametric comparisons of cardiac parameters after 4 weeks of exposure to isoproterenol and treatment with P188 in BL10 and mdx mice.
| Measurement | Group | N | Median | Range | Overall p-value | Significantly different groups |
|---|---|---|---|---|---|---|
| Heart rate (bpm) | BL10 - Untx | 3 | 450 | 421 - 476 | ||
| BL10 - Iso | 7 | 615 | 532 - 656 | |||
| MDX - Untx | 6 | 438 | 400 - 489 | 0.0004 | BL10-Iso vs. MDX-Untx (p = 0.0267) | |
| MDX - Iso | 9 | 585 | 541 - 667 | MDX-Untx vs. MDX-Iso (p = 0.0149) | ||
| MDX - Iso + P188 | 5 | 632 | 615 - 667 | |||
Bpm - beats per minute; iso - isoproterenol; untx - untreated