Table 3.

List of ribonucleases and their therapeutic applications.

Ribonuclease	Therapeutic role/potential role	Reference
hPNPaseold35	Prevents tumour cell division; drives tumour cells to apoptosis and senescence	Leszczyniecka et al. (2003)
	Successfully used as a neuroblastoma therapy	Van Maerken et al. (2009)
Onoconase	In clinical trials as an anti‐tumour therapy; promotes apoptosis of tumour cells	Ardelt et al. (2009)
RNase 7	Selectively inhibits Enterococcus faecium on human keratinocytes/skin application	Köten et al. (2009)
Dicer like enzymes/RNase III	Antiviral properties in fungal, plant and protozoan models	Sun et al. (2009); Lewsey and Carr (2009); Patrick et al. (2009)