Table 2.
Patient and tumor characteristics stratified by receipt of lymphadenectomy or adrenalectomy.
| Total | Lymphadenectomy | Adrenalectomy | |||||
|---|---|---|---|---|---|---|---|
| N | No (%)* | Yes (%)* | p** | No (%)* | Yes (%)* | p** | |
| TOTAL | 730 | 652 (89) | 78 (11) | 556 (76) | 174 (24) | ||
| PATIENT CHARACTERISTICS | |||||||
| Age at diagnosis (years) | |||||||
| 20 – 44 | 90 | 73 (81) | 17 (19) | 0.04 | 69 (77) | 21 (23) | >0.20 |
| 45 – 54 | 168 | 148 (88) | 20 (12) | 129 (77) | 39 (23) | ||
| 55 – 64 | 226 | 204 (90) | 22 (10) | 170 (75) | 56 (25) | ||
| 64 – 74 | 184 | 168 (91) | 16 (9) | 142 (77) | 42 (23) | ||
| 75 – 79 | 62 | 59 (95) | 3 (5) | 46 (74) | 16 (26) | ||
| Sex | |||||||
| Male | 414 | 374 (90) | 40 (10) | >0.20 | 297 (72) | 117 (28) | <0.01 |
| Female | 316 | 278 (88) | 38 (12) | 259 (82) | 57 (18) | ||
| Race | |||||||
| White | 543 | 488 (90) | 55 (10) | >0.20 | 410 (76) | 133 (24) | >0.20 |
| Black | 187 | 164 (88) | 23 (12) | 146 (78) | 41 (22) | ||
| Education | |||||||
| <= 11 years high school | 113 | 99 (88) | 14 (12) | >0.20 | 94 (83) | 19 (17) | 0.15 |
| High school grad or equivalent | 262 | 235 (90) | 27 (10) | 203 (77) | 59 (23) | ||
| 1–3 years college | 196 | 177 (90) | 19 (10) | 143 (73) | 53 (27) | ||
| 4 years college or more | 159 | 141 (89) | 18 (11) | 116 (73) | 43 (27) | ||
| Body Mass Index (BMI)a | |||||||
| <25 | 138 | 118 (86) | 20 (14) | >0.20 | 113 (82) | 25 (18) | >0.20 |
| 25 – <30 | 253 | 227 (90) | 26 (10) | 195 (77) | 58 (23) | ||
| 30 – <35 | 184 | 166 (90) | 18 (10) | 133 (72) | 51 (28) | ||
| 35+ | 149 | 135 (91) | 14 (9) | 110 (74) | 39 (26) | ||
| Smoking status | |||||||
| Never smoker | 260 | 227 (87) | 33 (13) | 0.20 | 192 (74) | 68 (26) | >0.20 |
| Occasional | 33 | 30 (91) | 3 (9) | 23 (70) | 10 (30) | ||
| Former smoker | 255 | 236 (93) | 19 (7) | 195 (76) | 60 (24) | ||
| Current smoker | 182 | 159 (87) | 23 (13) | 146 (80) | 36 (20) | ||
| TUMOR CHARACTERISTICS | |||||||
| Presence of renal cystsb | |||||||
| No | 482 | 433 (90) | 49 (10) | >0.20 | 369 (77) | 113 (23) | >0.20 |
| Yes | 238 | 209 (88) | 29 (12) | 177 (74) | 61 (26) | ||
| Tumor size (largest tumor)c | |||||||
| < 4 cm | 310 | 298 (96) | 12 (4) | <0.01 | 259 (84) | 51 (16) | <0.01 |
| 4 – 7 cm | 228 | 205 (90) | 23 (10) | 178 (78) | 50 (22) | ||
| > 7 cm | 183 | 140 (77) | 43 (23) | 114 (62) | 69 (38) | ||
| SEER Staged | |||||||
| Local | 571 | 530 (93) | 41 (7) | <0.01 | 453 (79) | 118 (21) | <0.01 |
| Regional | 125 | 97 (78) | 28 (22) | 80 (64) | 45 (36) | ||
| Distant | 33 | 24 (73) | 9 (27) | 23 (70) | 10 (30) | ||
| Histology | |||||||
| Clear cell | 549 | 492 (90) | 57 (10) | 0.01 | 409 (74) | 140 (26) | >0.20 |
| Papillary | 81 | 73 (90) | 8 (10) | 65 (80) | 16 (20) | ||
| Chromophobe | 46 | 44 (96) | 2 (4) | 37 (80) | 9 (20) | ||
| Cystic RCC | 37 | 32 (86) | 5 (14) | 32 (86) | 5 (14) | ||
| Other histologye | 17 | 11 (65) | 6 (35) | 13 (76) | 4 (24) | ||
| Tumor gradef | |||||||
| Well-differentiated | 67 | 65 (97) | 2 (3) | 0.06 | 54 (81) | 13 (19) | >0.20 |
| Moderately-differentiated | 239 | 215 (90) | 24 (10) | 182 (76) | 57 (24) | ||
| Poorly-differentiated | 150 | 130 (87) | 20 (13) | 106 (71) | 44 (29) | ||
| Undifferentiated | 47 | 39 (83) | 8 (17) | 32 (68) | 15 (32) | ||
| Fuhrman Grade (FG)g | |||||||
| FG 1 | 77 | 73 (95) | 4 (5) | <0.01 | 63 (82) | 14 (18) | 0.06 |
| FG 2 | 329 | 300 (91) | 29 (9) | 257 (78) | 72 (22) | ||
| FG 3 | 188 | 167 (89) | 21 (11) | 131 (70) | 57 (30) | ||
| FG 4 | 48 | 35 (73) | 13 (27) | 33 (69) | 15 (31) | ||
*
Row percentages;
**
p-value evaluating for association between patient/tumor characteristics and surgical approach (ORN vs LRN);
a
6 cases missing/unknown;
b
10 cases missing/unknown;
c
9 cases missing/unknown;
d
1 case missing/unknown;
e
other histologies include acidophil carcinoma, sarcomatoid renal cell carcinoma, collecting duct carcinoma, and granular cell carcinoma;
f
227 cases missing/unknown;
g
88 cases missing/unknown