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wuc is a homologue of lin52. T-Coffee alignment of Wuc predicted protein sequence with Lin52 from D. melanogaster, C. elegans and H. sapiens. Residues conserved or identical in at least 2/4 sequences are highlighted. The Wuc amino acids mutated in the EMS screen (Supplementary material) are indicated with asterisks. The region used for RNAi knockdown is underlined, and the sequence included in the shortest yeast 2-hybrid clones is double underlined.
