Table 3. Systematic review results on primary endpoint.

RCT	Endpoint	NPWT	Control	p value	Evidence
Commercially available systems
Blume 2008 (8)	No. of cases of complete wound closure; n (%)	73 (43)	48 (29)	p = 0.007	Observation period 112 days; no data on 6 or 9 month follow-up
Chio 2010 (9)	n/a	n/a	n/a	n/a	–
Keskin 2008 (10)	n/a	n/a	n/a	n/a	–
Stannard 2009 (11)	n/a	n/a	n/a	n/a	–
Systems not commercially available
Bee 2008 (12)	Abdominal wall closed by sewing together the fascia; n(%)	15 (31)	5 (26)	Insig.	Unclear figures in Table 2 of article: closure (total) 14 (48) but NPWT + control = 20 (70). No confidence interval or p value stated in article, only qualitative interpretation: no difference
Mody 2008 (13)	No. of cases of complete wound closure; n (%)	7 (48)	16 (48)	n/a	Percentages relate to no. of patients treated, not no. of patients randomized; few patient characteristics reported
Perez 2010 (14)	No. of cases of complete wound closure; n (%)	18 (90)	19 (95)	p = 0.302	30 days after wound closure or skin transplantation
Saaiq 2010 (15)	No. of cases of complete wound closure; n (%)	45 (90)	9 (18)	p <0.001	2 weeks after skin transplantation; 3 categories (2 weeks, 3 to 4 weeks and 5 or more weeks) instead of mean no. of days to wound healing
Sepúlveda 2009 (169)	n/a	n/a	n/a	n/a	–

RCT: randomized controlled trial; –: None; n/a: not available; Insig.: statistically insignificant; NPWT: negative-pressure wound therapy