eTable 4. Categories of wounds in included RCTs.

RCT	Chronic open				Acute open						Covered
	Arteriosclerotic, diabetic ulcers	Chronic venous ulcers	Pressure sores	Other	Foot amp.	Post-trauma	Open abdominal	Fasciitis	Skin graft	Other	Split-skin graft
Commercially available systems
Blume 2008 (8)	+	–	–	–	–	–	–	–	–	–	–
Chio 2010 (9)	–	–	–	–	–	–	–	–	+	–	–
Keskin 2008 (10)	–	–	–	–	–	+	–	–	–	–	–
Stannard 2009 (11)	–	–	–	–	–	+	–	–	–	–	–
Systems not commercially available
Bee 2008 (12)	–	–	–	–	–	–	+	–	–	–	–
Mody 2008 (13)	+	–	+	–	–	–	–	+	–	+	–
Perez 2010 (14)	+	+	–	+	–	+	–	+	–	+	–
Saaiq 2010 (15)	–	–	–	–	–	–	–	–	–	–	+
Sepúlveda 2009 (16)	–	–	–	–	+	–	–	–	–	–	–

RCT: randomized controlled trial; + Yes; – No; amp.: Amputation; NPWT: Negative-pressure wound therapy; post-trauma: post-traumatic wounds