Table 1.
Airflow, Aerosol, and Wall Conditions of the Four Cases Considered
| Cases | Aerosol inlet (right nostril) | Humidity inlet (left nostril) | Wall conditions |
|---|---|---|---|
| 1 (EXP/CFD) | Q: 10 L/min | Q: 20 L/min | Twall : 37°C |
| T: 37°C | T: 25°C | RHwall : 0%a | |
| RH: 99% | RH: 100% | ||
| MMAD = 4.67 (0.05) μm | |||
| n = 3.0 × 105 part/cm3> | |||
| 2 (EXP/CFD) | Q: 10 L/min | Q: 20 L/min | Twall : 37°C |
| T: 21°C | T: 39°C | RHwall : 100% | |
| RH: 97.5% | RH: 100% | ||
| MMAD = 900 (32.7) nm | |||
| n = 2.8 × 105 part/cm3 | |||
| 3 (CFD)b | Q: 15 L/min | Q: 15 L/min | Twall : 37°C |
| T: 35°C | T: 39°C | RHwall : 100% | |
| RH: 95% | RH: 100% | ||
| MMAD = 560 (11.4) nm | |||
| and 900 (32.7) nm | |||
| 4 (CFD)b | Q: 15 L/min | Q: 15 L/min | Twall : 37°C |
| T: 35°C | T: 42°C | RHwall : 100% | |
| RH: 95% | RH: 100% | ||
| MMAD = 560 (11.4) nm | |||
| and 900 (32.7) nm |
a
Humidified air was insufficient to wet the airway walls in the experiment for Case 1. Dry walls were included in the CFD simulation to match the in vitro conditions.
b
CFD simulations were used to explore the effects of modifying the aerosol and humidity inlet conditions.