Table 2.
Nine-Gene Predictor of Prostate Cancer Recurrence Following Surgery
| Symbol | Description | Coefficient | References |
|---|---|---|---|
| RAD23B | RAD23 homolog B | 0.152 | 20, 21 |
| FBP1 | Fructose-1,6-bisphosphatase 1 | 0.310 | 7, 10, 33 |
| TNFRSF1A | Tumor necrosis factor receptor superfamily, member 1A | −0.560 | 23, 24 |
| NOTCH3 | Notch homolog 3 | 0.426 | 25, 26 |
| ETV1 | Ets variant gene 1 (ETV1) | 0.157 | 9, 15 |
| BID | BH3 interacting domain death agonist (BID) | 0.248 | 27, 28 |
| SIM2 | Single-minded homolog 2 | 0.043 | 29–32 |
| ANXA1 | Annexin A1 | −0.185 | 33–36 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.028 | 37–38 |
Coefficient is derived from the lasso Cox proportion hazards model and was used for computing the predictive score. Positive coefficients indicate a positive association with recurrence, and negative coefficients indicate a negative association with recurrence.