Isolated cardiac complex I (A), complex II-III (B), complex V (C), citrate synthase (D), and aconitase activities (E) at 1, 3, 7, and 14 days after intraperitoneal DOM administration (gray bars) in rats, compared with 1 and 14 days after saline administration in controls (black bars). Data are expressed as means ± SEM of 8 separate experiments. †P < 0.05, ††P < 0.01, †††P < 0.001 versus 1-day saline; ‡P < 0.05, ‡‡P < 0.01, and ‡‡‡P < 0.001 versus 14-day saline.