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. 2011 Jul;179(1):180–188. doi: 10.1016/j.ajpath.2011.03.018

Figure 6.

Figure 6

Increased collagen deposition correlates with increased fibroblasts, increased ArgI expression and activity, and decreased NO production in SHIP–/– mouse distal ilea. A: Masson's trichrome staining (blue, left) and anti-vimentin labeling (red, right; DAPI, blue) in ileal cross sections from SHIP+/+ and SHIP–/– mice. Scale bars = 50 μm. B: IHC analysis of ArgI (brown, left) and nitrotyrosine (pink/red, right) levels in serial sections from SHIP+/+ and SHIP–/– mouse ilea (hematoxylin, blue). Scale bars = 100 μm. C: ArgI activity in SHIP+/+ and SHIP–/– mouse ilea. Bars represent the mean ± SD for 6 to 12 mice at each age (*P < 0.05).