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Targeted deletion of Jund and glomerular expression of hypoxia-induced genes. Glomerular expression of Vegfa (A), Cxcr4 (B), Cxcl12 (C), and fibronectin (D) in unmanipulated (basal) and NTN-induced (NTN) WT and Jund-/- mice assessed by RT-qPCR. Targeted deletion of Jund did not significantly affect the expression of other AP-1 members, such as c-Fos (E) and c-Jun (F). Six mice were used in each group. ns indicates nonsignificant. *P < 0.05, **P < 0.01.
