Figure 4.

Whole-cell Ca currents and Ca concentrations in the ventricular myocyte model paced at 1 Hz. (A) AP. (B) L-type Ca current $\left({\mathrm{I}}_{\mathrm{CaL}}^{\mathrm{cell}}\right).$ (C) Ca release flux from SR $\left({\mathrm{J}}_{\mathrm{rel}}^{\mathrm{cell}}\right).$ (D) Average Ca concentration in the dyadic space $\left(\mathrm{C}{\mathrm{a}}_{\mathrm{d}}^{\mathrm{cell}}\right).$ (E) CaT in the myoplasm $\left(\mathrm{C}{\mathrm{a}}_{\mathrm{i}}^{\mathrm{cell}}\right).$ (F) Average free Ca concentration in the SR $\left(\mathrm{C}{\mathrm{a}}_{\mathrm{SR}}^{\mathrm{cell}}\right).$ Insets in C and D show expanded timescale.