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. 2011 Jun 22;100(12):2929–2935. doi: 10.1016/j.bpj.2011.05.003

Figure 3.

Figure 3

Typical traces of the ion current through single αHL channels in the presence of PEG1294 in the bath solution at a time resolution of 0.1 ms. (Arrows) Voltage shift from zero to 40 mV. Halide concentration was 4 M. Concentration of PEG was 400 μM (for A–C) and 10 nM (for panel D). Note the change in the timescale and PEG concentration from panels A–D. The respective all-point histograms are shown at the right of each record and used to give the mean value of blockage amplitudes. The effectiveness of such inhibition was very similar for all halides and comprised 73–80% of the maximal current.