Figure 5.

Cytokine and chemokine levels in serum samples from patients with EM. Serum samples were available from 28 patients with EM from whom the isolates were obtained. Protein expression of cytokines and chemokines was determined using multiplex assays from all serum samples in one complete experiment. Patient serum samples were subdivided according to the RST type of the infecting strain (8 RST1, 10 RST2, and 10 RST3) (A) or the three most common OspC types (B). C: Patient samples were subdivided into two equally sized groups based on the number of symptoms. Inset: The percentage of isolates in each RST group associated with either 0 to 3 or 4 to 20 symptoms. The box represents 25^th to 75^th percentiles; lines outside the box, 5^th to 95^th percentiles; and horizontal line in the box, median. *P ≤ 0.05.