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. 2011 Jun;178(6):2726–2739. doi: 10.1016/j.ajpath.2011.02.018

Table 1.

Clinical Findings in Patients with EM According to Isolate Genotype

Species and genotype Total isolates EM
No. of patients with hematogenous dissemination No. of symptoms [median (range)]
Median size (cm) Median duration (days)
B. burgdorferi 30 10 3 15 5.0 (0–20)
 RST1 10 10 3 6 8.5 (3–11)
  OspC type A 10 10 3 6 8.5 (3–11)
 RST2 10 12 4 6 1.5 (0–20)
  OspC type F 1 18 3 0 2.0 (2)
  OspC type N 2 14 6 1 0.5 (0–1)
  OspC type K 7 12 3 5 3.0 (0–20)
 RST3 10 10 3 3 6.5 (0–10)
  OspC type D 1 8 7 1 0.0 (0)
  OspC type E 2 10 4 1 9.0 (8–10)
  OspC type G 2 12 4 0 4.5 (0–9)
  OspC type I 5 9 3 1 6.0 (2–9)

Hematogenous dissemination in patients with EM was based on a positive PCR result in blood or multiple EM lesions.

The number of symptoms in patients with RST1 infection was significantly greater than in patients with RST2 infection (P = 0.01).