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. 2011 Jun;178(6):2888–2896. doi: 10.1016/j.ajpath.2011.02.013

Figure 1.

Figure 1

Effect of GTN on hypoxia-induced increases in sFlt-1 and sEng mRNA levels in chorionic villi explants. (minimum of three placentas per treatment) A: Quantitative PCR (qPCR) analysis of Flt-1 mRNA levels (expressed as the ratio of spliced Flt-1/receptor Flt-1 mRNA forms). Transcript levels were normalized against β-actin mRNA levels. B: qPCR analysis of sEng; mRNA levels were quantified relative to β-actin transcript levels. Error bars represent SEM. ***P < 0.001. Transverse lines link two groups to indicate statistical significance.