Table 1.
P | |||
---|---|---|---|
WT→Ldlr−/− | Fas−/−→Ldlr−/− | value | |
Body weight (g) | 19.7 ± 1.3 | 20.2 ± 0.6 | NS |
Spleen weight (mg) | 108.9 ± 28.3 | 108.9 ± 39.8 | NS |
Spleen/body weight (mg/g) | 5.6 ± 1.3 | 5.4 ± 1.9 | NS |
Lymphadenopathy | Not detected | Not detected |
Lymphoproliferation parameters were assessed in WT→Ldlr−/− (n = 15) and Fas−/−→Ldlr−/− (n = 11) chimeric mice after 16 weeks on an 0.5% cholesterol diet. Data are reported as means ± SD; NS, not significant.