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. 2011 Jun;178(6):2931–2937. doi: 10.1016/j.ajpath.2011.02.011

Table 1.

Absence of Lymphoproliferation in Hematopoietic Fas−/−Ldlr−/− Chimeric Mice

P
WT→Ldlr−/− Fas−/−Ldlr−/− value
Body weight (g) 19.7 ± 1.3 20.2 ± 0.6 NS
Spleen weight (mg) 108.9 ± 28.3 108.9 ± 39.8 NS
Spleen/body weight (mg/g) 5.6 ± 1.3 5.4 ± 1.9 NS
Lymphadenopathy Not detected Not detected

Lymphoproliferation parameters were assessed in WTLdlr−/− (n = 15) and Fas−/−Ldlr−/− (n = 11) chimeric mice after 16 weeks on an 0.5% cholesterol diet. Data are reported as means ± SD; NS, not significant.