Figure 1.
IHC detection of BAG3 in human glial brain tumors. A: BAG3 is detected in the cytoplasm of neoplastic astrocytes, and its expression significantly increases according to the tumor grade, but is barely detectable in the normal brain. Original magnification, ×400 (all images). B: The percentages of BAG3-positive cells were evaluated in all specimens from tumors of the same grade and the mean percentage ± SE was calculated. *P < 0.05 versus grade I; ***P < 0.001 versus grade II.