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. 2011 Jun;178(6):2536–2546. doi: 10.1016/j.ajpath.2011.02.045

Figure 5.

Figure 5

Increased elastin deposition in lungs from VEC Cx43−/−/Cx40−/− mice. Paraffin-embedded distal lung sections from C57Bl/6 (A, E, I, and M), VEC Cx43−/− (B, F, J, and N), Cx40−/− (C, G, K, and O), and VEC Cx43−/−/Cx40−/− (D, H, L, and P) mice at age 8 weeks (A–D), 16 weeks (E–H), 24 weeks (I–L), or 32 weeks (M–P) were labeled using Verhoeff to stain elastin fibers dark brown, and were imaged. Compared with the other strains examined, lungs from VEC Cx43−/−/Cx40−/− mice showed increased elastin labeling (arrowheads). Scale bars = 60 μm.