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. 2011 Jun;178(6):2690–2699. doi: 10.1016/j.ajpath.2011.02.035

Figure 8.

Figure 8

Deletion of PPARγ with a Cre-expressing adenovirus. Stellate cells were isolated from WT and PPARγ Cre/Lox mice and grown in culture. After 48 hours, cells were infected with adenovirus expressing Cre and/or lentivirus encoding adiponectin or corresponding control for 4 days. Total cellular RNA was isolated and mRNA expression of PPARγ was quantified by RT-PCR (means ± SE; n = 3). *P < 0.05 versus WT cells exposed to adenovirus expressing GFP alone; **P < 0.05 versus Lox/Lox cells exposed to adenovirus expressing GFP alone.