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. Author manuscript; available in PMC: 2012 Jun 20.
Published in final edited form as: Chem Res Toxicol. 2011 May 18;24(6):968–978. doi: 10.1021/tx2001459

Figure 5.

Figure 5

Mass chromatograms of the target ions of THMA (a), HHMA (b), and HMMA (c). Top chromatograms of each part (a–c) show given ions in rat brain tissue spiked with THMA, HHMA, and HMMA, respectively. Final tissue concentration of each spiked analyte was 5 μg/g. Bottom chromatograms of each part (a–c) show given ions in an authentic brain tissue samples taken from rats (N=3) treated with a high neurotoxic dose of MDMA (80 mg/kg; SC) three hours previously. Similar results were obtained in rats treated identically but sacrificed 1.5 (instead of 3) hr after drug administration.