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. Author manuscript; available in PMC: 2012 Jun 20.
Published in final edited form as: Chem Res Toxicol. 2011 May 18;24(6):968–978. doi: 10.1021/tx2001459

Figure 7.

Figure 7

5-HT levels and 5-HIAA levels in ipsilateral frontal cortex of rats two weeks after cortical administration of 42 nmol 6-NAC-THMA. The thioether conjugate was injected four times, with a 12-h interval between each injection. 6-NAC-THMA was dissolved in aCSF shortly before each injection. Control animals received unilateral intraparenchymal injections of an equivalent volume of aCSF. A positive control group consisted of animals that received a single intraparenchymal injection of 52 nmol of 5, 7-DHT. Values represent the mean ±SD (N=8 in 6-NAC-THMA groups, N=6 in positive control groups, and N=6 in control groups). One-way ANOVA followed by Tukey’s multiple comparison test was performed and differences regarded as significant when p<0.05. * Indicates significant different from control group.