Figure 2. The frequency of κTg B cells and serum κTg Ig in chimeras is proportional to the frequency of donor κTg BM cells.
A, Percent ofκTg B cells among B220+ splenocytes from representative mixed BMC. B, Mean percent of κTg B cells in primary and secondary lymphoid organs. Mean percentages were obtained after subtracting values observed in the CA30-only chimeras. C, Mean total κTg Ig concentrations in sera of mixed chimeras. κTg-F1 denotes pooled sera of 3 κTg mice. D, Mean total Igκ concentration (IgMκ + IgGκ) in mixed chimeras. Error bars indicate mean plus SEM for n=5 mice per group. * Indicates undetectable.