Table 5.
Middle molecular weight solute removal
| Dialyser |
|||
|---|---|---|---|
| Xevonta Hi 23 | FX 100 | Xenium 210 | |
| Amembris® | Helixone® | Purema® | |
| β2m | |||
| Blood before (mg/L) | 18.4 ± 0.4 | 19.3 ± 0.4 | 18.6 ± 0.4 |
| Corrected blood after (mg/L) | 6.6 ± 0.3 | 8.0 ± 0.3 | 7.5 ± 0.3a,b |
| Blood RR (%) | 64.3 ± 0.9 | 58.9 ± 1.0 | 59.9 ± 1.1a,b |
| Dialysate concentration (mg/L) | 1.29 ± 0.05 | 1.14 ± 0.07 | 0.99 ± 0.05b |
| Total dialysate mass (mg) | 146 ± 6 | 130 ± 8 | 110 ± 7b,c |
| K (mL/min) | 51 ± 3 | 54 ± 3 | 30 ± 2b,c |
| Leptin | |||
| Blood before (μg/L) | 34.7 ± 12.3 | 43.0 ± 17.5 | 26.0 ± 6.5 |
| Corrected blood after (mg/L) | 15.4 ± 5.1 | 18.2 ± 7.0 | 13.4 ± 2.9 |
| Blood RR (%) | 31.8 ± 4.7 | 27.7 ± 5.2 | 28.7 ± 4.4 |
| RBP | |||
| Blood before (mg/L) | 195.5 ± 26.6 | 160.4 ± 15.0 | 206.9 ± 20.5 |
| Corrected blood after (mg/L) | 142.2 ± 18.2 | 126.0 ± 13.6 | 163.9 ± 14.7 |
| Blood RR (%) | 22.4 ± 4.0 | 20.6 ± 4.1 | 18.2 ± 2.5 |
| Dialysate concentration (mg/L) | 1.58 ± 0.20 | 1.19 ± 0.14 | 0.90 ± 0.07b |
| Total dialysate mass (mg) | 179.4 ± 23.4 | 136.5 ± 16.3 | 104.4 ± 8.7b |
| K (mL/min) | 7.0 ± 1.2 | 4.8 ± 0.6 | 3.2 ± 0.4b |
| α1-Antitrypsin | |||
| Blood before (g/L) | 1.53 ± 0.05 | 1.50 ± 0.05 | 1.42 ± 0.04 |
| Corrected blood after (mg/L) | 1.38 ± 0.04 | 1.36 ± 0.04 | 1.29 ± 0.04 |
| Blood RR (%) | 9.4 ± 0.9 | 8.9 ± 1.0 | 8.7 ± 0.9 |
| Albumin | |||
| Blood before (g/L) | 36.9 ± 0.5 | 36.5 ± 0.5 | 36.7 ± 0.4 |
| Corrected blood after (g/L) | 33.6 ± 0.6 | 33.0 ± 0.5 | 33.5 ± 0.5 |
| Blood RR (%) | 9.0 ± 0.9 | 9.2 ± 0.9 | 8.7 ± 0.8 |
| Dialysate concentration (mg/L) | 1.19 ± 0.14 | 0.80 ± 0.09 | 0.66 ± 0.04a,b |
| Total dialysate mass (mg) | 133.1 ± 15.7 | 89.4 ± 9.3 | 71.4 ± 5.4a,b |
| K (mL/min) | 0.017 ± 0.003 | 0.017 ± 0.003 | 0.008 ± 0.001b,c |
| Total proteins | |||
| Blood before (g/L) | 64.6 ± 0.8 | 61.4 ± 0.8 | 64.1 ± 0.7a,c |
| Corrected blood after (g/L) | 58.7 ± 0.9 | 55.8 ± 0.7 | 58.5 ± 0.7a,c |
| Blood RR (%) | 9.0 ± 0.8 | 8.8 ± 1.0 | 8.6 ± 0.9 |
| Dialysate concentration (mg/L) | 10.7 ± 0.7 | 7.1 ± 0.5 | 7.6 ± 0.4a,b |
| Total dialysate mass (mg) | 1209 ± 74 | 810 ± 55 | 809 ± 52a,b |
| K (mL/min) | 0.09 ± 0.01 | 0.08 ± 0.01 | 0.05 ± 0.01b,c |
a
P < 0.05 Xevonta vs FX.
b
P < 0.05 Xevonta vs Xenium.
c
P < 0.05 FX vs Xenium.