A: Immunoblots for LC3 in liver lysates obtained from controls with no or mild abnormalities at liver histological examination (n = 5), from patients with nonalcoholic steatohepatitis (NASH) or alcoholic liver disease (n = 4; no fibrosis, n = 3; septal fibrosis, n = 1), with chronic hepatitis B (n = 6; fibrosis stage according to the METAVIR score: F1, n = 4; F2, n = 1; F4, n = 1), and with chronic hepatitis C (n = 5; fibrosis stage according to METAVIR score: F1, n = 3; F2, n = 2). The protein expression was normalized with β-actin. Box plots represent median, quartiles, and ranges. *P < 0.05. Fibrosis stage (METAVIR): F0 (absent), F1 (portal fibrosis), F2 (portal fibrosis with few septa), F3 (septal fibrosis), F4 (cirrhosis). B: Representative LC3 immunoblots.