Table 1.
Subject demographics.
| Subject ID | Gestational age at birth (weeks) | Birth weight (grams) | Postnatal age (days) | Postmenstrual age (weeks) | Anasarca | Extracorporeal membrane oxygenation |
|---|---|---|---|---|---|---|
| Neonates | ||||||
| 1 | 39 | 3730 | 2 | 39 | - | X |
| 2 | 26 | 770 | 7 | 27 | - | - |
| 3 | 26 | 980 | 7 | 27 | - | - |
| 4 | 27 | 1180 | 11 | 29 | - | - |
| 5 | 27 | 1060 | 13 | 29 | - | - |
| 6 | 27 | 915 | 17 | 29 | - | - |
| 7 | 36 | 2345 | 24 | 39 | X | X |
| 8 | 39 | 3653 | 28 | 43 | - | - |
| Median | 27 | 1120 | 12 | 29 | ||
| Range | 26–39 | 770–3730 | 2–28 | 27–43 | ||
| Infants | ||||||
| 9 | 35 | 2080 | 50 | 42 | - | - |
| 10 | 37 | - | 68 | 47 | - | - |
| 11 | 40 | 3700 | 104 | 55 | - | - |
| 12 | 37 | 2100 | 105 | 52 | - | - |
| 13 | 39 | 3969 | 169 | 63 | - | - |
| 14 | 24 | 660 | 197 | 52 | X | - |
| 15 | 38 | 3856 | 451 | 102 | X | - |
| Median | 37 | 2900 | 105 | 52 | ||
| Range | 24–40 | 660–3969 | 50–451 | 42–102 | ||
| Total median | 36 | 2090 | 28 | 42 | ||
| Total range | 24–40 | 660–3969 | 2–451 | 27–102 |
Subject #12 died soon after administration of first dose of study drug