Intracellular accumulation of DNR in K562/A02 cells incubated for 48 hours by flow cytometry assay. A) Intracellular fluorescence intensity associated with DNR in treated cells. a) Control, b) DNR-Sol, c) DNR/Br Tet-Sol, d) DNR-MNPs, e) DNR/Br Tet-MNPs; B) RFI of DNR in treated cells.
Abbreviations: DNR-Sol, daunorubicin in solution; DNR/Br Tet-Sol, daunorubicin and 5-bromotetrandrin in solution; DNR-MNPs, daunorubicin in magnetic nanoparticles; DNR/Br Tet-MNPs, daunorubicin and 5-bromotetrandrin in magnetic nanoparticles; FI, fluorescence intensity; RFI, relative fluorescence intensity.