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H&E stained skin sections in an acute toxicity study (× 40). A) Negative control; B) AgNO3 group: reduced thickness of epidermis and increased regular collagen fiber in papillary layer and mononuclear inflammation; C) Low-dose nanosilver group with reduced thickness of epidermis, reduced thickness of papillary layer, and regular collagen fibers; D) High-dose nanosilver group with reduced thickness of epidermis, reduced thickness of papillary layer, and irregular collagen fibers.
