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Dermal histopathologic changes in subchronic test
| Group | Inflammation | Round cell | Clear cell | Decreased epidermis | Decreases collagen fiber | Decreased lamina propria attachments |
|---|---|---|---|---|---|---|
| Control | − | − | − | − | − | − |
| AgNO3 | + | − | + | + | + | − |
| Nanosilver 100 μg/mL | + | − | + | + | + | − |
| Nanosilver 1000 μg/mL | + | + | + | + | ++ | − |
| Nanosilver 10,000 μg/mL | + | ++ | ++ | ++ | +++ | ++ |
Notes: Severe (+++); moderate (++); mild (+); none (−).
