Table 4.
Results for rs1062923-PM2.5 interactions 7 day moving averages†
| Endothelial Marker | Number of participants | % change (95% CI) | Unadjusted p-value For interaction | Adjusted p-value |
|---|---|---|---|---|
| sICAM-1 homozygous carriers | 31 | -9.0 (-15.0, -2.5) | 0.0002* | 0.004* |
| Wild-type and heterozygotes | 686 | 3.4 (1.9, 4. 9) | ||
| sVCAM-1 homozygous carriers | 31 | -9.2 (-17.2,-0.5) | 0.005 | 0.1 |
| Wild-type and heterozygotes | 686 | 2.8 (0.9, 4.8) | ||
†IQR change in7 day moving average of PM2.5 = 4.27 μg/m3
*models adjusted for education (≤12 years, 13-16 years, >16 years), ≥2 alcoholic drinks per day, age at first adhesion molecule measurement, time since first measurement, body mass index (BMI), diabetes diagnosi or fasting glucose >126 mg/dL, smoking status, pack-years smoked, hypertension medication use (yes/no), statin use, apparent temperature, seasonality (sine and cosine of month), CRP >10 mg/L.