Table 1.
RAG1 Domain | Conditions | Zinc:Protein Ratio ICP-MSa,b | Zinc:Protein Ratio FAASa,b |
---|---|---|---|
CNDc | Zinc Free Buffer | 2.08 ± 0.68 | 2.00 ± 0.44 |
CNDc | DTPA Buffer | 0.24 ± 0.14 | 0.37 ± 0.29 |
bZDDd | Zinc Free Buffer | 4.23 ± 0.65 | 4.12 ± 0.78 |
a The zinc content of each construct was determined using ICP-MS and FAAS.
b Data presented represent the average of two or more independent experiments.
c Zinc binding results for mbp-CND and tagless CND were comparable. The results presented for CND represent the average from both data sets.
d Zinc binding for bZDD was evaluated for the mbp-tagged construct only.