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. 2011 Jun 27;6(6):e20511. doi: 10.1371/journal.pone.0020511

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Zhang, Pugh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A composite distribution of H2Av nucleosomal sequence tags is shown around the start (left panel) and end (right panel) of DNA TIR elements. Euchromatic elements are shown in the gray-filled plot and heterochromatic elements are indicated by the black trace. The relative location of TIR ends is shown as a black filled plot. The structure of the TIREs, drawn to approximate scale is shown above the plot. Multiple sequence alignments of TIREs is shown above the schematic, illustrating the proposed location of an H2Av nucleosome. Many TIREs are degenerate, lacking the internal homology regions to the transposon, and lacking a matching downstream inverted repeat.