Table 1. Distributions of select variables in breast cancer cases and cancer-free controls.
Variables | Stage 1 | Stage 2 | Combined | Combined | |||
case(N = 878) | control(N = 900) | case(N = 914) | control(N = 967) | case(N = 1792) | control(N = 1867) | P value | |
Age, year (mean ± SD) | 51.29±11.38 | 51.47±11.67 | 50.11±11.36 | 48.64±12.28 | 50.69±11.38 | 50.01±12.07 | 0.077 |
Age at menarche, year (mean ± SD)a | 15.25±1.85 | 15.85±1.90 | 15.18±1.96 | 16.24±1.81 | 15.21±1.90 | 16.05±1.86 | <0.0001 |
Age at first live birth, year (mean ± SD)b | 25.65±3.48 | 24.90±3.40 | 25.55±3.16 | 24.15±2.58 | 25.60±3.32 | 24.51±3.03 | <0.0001 |
Age at natural menopause, year (mean ± SD)c | 49.85±3.18 | 49.15±4.09 | 49.71±3.72 | 49.69±3.56 | 49.78±3.45 | 49.42±3.84 | 0.051 |
Menopausal status | <0.0001 | ||||||
Premenopausal | 416 | 437 | 434 | 530 | 850 | 967 | |
Natural menopause | 386 | 432 | 379 | 418 | 765 | 850 | |
Unnatural menopause | 58 | 16 | 84 | 9 | 142 | 25 | |
Estrogen receptor (ER) | |||||||
Positive | 369 | 434 | 803 | ||||
Negative | 321 | 322 | 643 | ||||
Progesterone receptor (PR) | |||||||
Positive | 396 | 414 | 810 | ||||
Negative | 294 | 340 | 634 |
Age at menarche information was available in 862 breast cancer cases and 896 controls (stage 1), 893 breast cancer cases and 962 controls (stage 2).
Age at first live birth information was available in 830 breast cancer cases and 872 controls (stage 1), 850 breast cancer cases and 943 controls (stage 2).
Age at natural menopause information was available in 380 breast cancer cases and 411 controls (stage 1), 363 breast cancer cases and 398 controls (stage 2).