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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Apr 18;20(5):1050–1055. doi: 10.1158/1055-9965.EPI-11-0176

Table 1.

Examples of symptom management and survivorship studies accruing through the NCI Cooperative Groups or CCOPS

Cooperative group and research base Study title(s)
Cancer and Leukemia Group B (CALGB)

  1. Phase III double blind trial of oral Duloxetine for treatment of pain associated with chemotherapy-induced peripheral neuropathy (CIPN) CALGB 170601

  2. A randomized study to prevent lymphedema in women treated for breast cancer CALGB 70305

  3. Development of a geriatric assessment measure for older patients with cancer CALGB 360401

  4. Collection of patient reported symptoms and performance status via the Internet CALGB 70501
Children’s Oncology Group (COG) A group-wide, prospective study of ototoxicity assessment in children receiving cisplatin chemotherapy
COG-ACCL05C1
Eastern Cooperative Oncology Group (ECOG)

  1. SOAPP (Symptom Outcomes and Practice Patterns): A survey of disease and treatment- related symptoms in patients with invasive cancer of the breast, prostate, lung, or colon/rectum

    ECOG-E2Z02

  2. Phase III randomized placebo-controlled trial to determine efficacy of Levocarnitine for fatigue in patients with cancer

    ECOG-E4Z02

  3. Quality of life in younger breast cancer survivors

    ECOG-E2Z04
Gynecologic Oncology Group (GOG) A prospective study of cognitive function during chemotherapy for front-line treatment of ovarian, primary peritoneal or fallopian tube cancer
GOG-0256
SunCoast CCOP Research Base at the University of South Florida

  1. Stress management therapy for patients undergoing chemotherapy

    SCUSF-0501

  2. Thyroid function and breast cancer: A pilot study to estimate prevalence of thyroid dysfunction in women diagnosed with breast cancer and the magnitude of change in thyroid function post-chemotherapy

    SCUSF-0502
North Central Cancer Treatment Group (NCCTG)

  1. The use of topical Baclofen, Amitriptyline, HCI, and Ketamine (BAK) in a PLO gel vs. placebo for the treatment of chemotherapy induced peripheral neuropathy: A phase III randomized double-blind placebo-controlled study

    NCCTG-N06CA

  2. A phase III, randomized, double-blind, placebo-controlled evaluation of Pregabalin for alleviating hot flashes

    NCCTG-N07C1

  3. Pilocarpine for vaginal dryness: a phase III double-blind RCT

    NCCTG-N04CA
National Surgical Adjuvant Breast and Bowel Project (NSABP) Patient reported outcomes in long-term survivors with colon and rectal cancer
NSABP LTS-01
Radiation Therapy Oncology Group (RTOG)

  1. A phase III international randomized trial of single vs. multiple fractions for re-irradiation of painful bone metastases

    RTOG-0433

  2. A randomized, double-blinded, placebo- controlled phase III trial to evaluate the effectiveness of a phosphodiesterase 5 inhibitor, Tadalafil, in prevention of erectile dysfunction in patients treated with radiotherapy for prostate cancer

    RTOG-0831
Southwest Oncology Group (SWOG)

  1. Randomized placebo-controlled trial of Acetyl-L-Carnitine (ALC) for the prevention of Taxane induced neuropathy phase III

    SWOG-S0715

  2. Companion long-term follow up study of men diagnosed with prostate cancer

    SWOG-0437

  3. Phase III trial of LHRH analog admin during chemotherapy to reduce ovarian failure following chemo in early stage hormone- negative breast cancer

    SWOG-S0230

  4. RCT assessing the effects of exercise on patients with locally advanced lung cancer undergoing curative intent combined modality therapy

    SWOG-S0229
University of Rochester Cancer Center (URCC) CCOP

  1. Yoga for persistent sleep disturbance in cancer survivors

    URCC 04-01

  2. A study of the effects of exercise on cancer- related fatigue

    URCC 08106