Table 2.

Listing of the 10 genes with the greatest change in expression in the human colon during acute E. histolytica colitis compared to convalescence. RNA was isolated from colonic biopsy samples, and gene transcripts were analyzed for microarray using the Affymetrix Human GeneChip® 1.0 ST chips.

	Day 1 mean expression (Log2) (±SEM)	Day 60 mean expression (Log2) (±SEM)	Fold change	p-value
REG1B	9 (1.02)	5.59 (0.23)	10.65	0.006
REG1A	10.69 (0.76)	7.8 (0.22)	7.4	0.003
MMP3	8.04 (0.73)	5.49 (0.17)	5.86	0.004
S100A8	8.28 (0.87)	6.08 (0.17)	4.59	0.026
MMP1	8.85 (0.62)	6.8 (0.26)	4.14	0.008
DMBT1	11.43 (0.22)	9.51 (0.46)	3.8	0.002
CHI3L1	8.3 (0.50)	6.48 (0.19)	3.54	0.004
AQP8	8.89 (0.67)	10.6 (0.33)	3.28	0.039
SLC26A2	9.59 (0.56)	11.11 (0.17)	2.88	0.022
OLFM4	12.16 (0.25)	10.76 (0.38)	2.64	0.009