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. Author manuscript; available in PMC: 2012 Jun 27.
Published in final edited form as: J Chem Inf Model. 2011 Jun 2;51(6):1307–1314. doi: 10.1021/ci200097m

Figure 5.

Figure 5

The pharmacophores for HSP90 (left) and FXIa (right) generated using MOE (top) and Pharmer (bottom). Hydrogen acceptor features are cyan in MOE and orange in Pharmer. Hydrogen donor features are magenta in MOE and white and Pharmer. Hydrophobic features are green and MOE and Pharmer position these features slightly differently. The hydrogen donor feature of HSP90 has a radius of 1.25Å, the hydrophobic feature of HSP90 has a radius of 2Å, the hydrophobic feature of FXIa has a radius of 1.5Å, and all other features have a radius of 1Å.