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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Toxicon. 2011 May 11;58(1):62–67. doi: 10.1016/j.toxicon.2011.05.003

Table 1.

Mouse intraperitoneal and oral LD50 for purified BoNT/B holotoxin and complex

BoNT/B ip LD50 (ng/kg)b Oral LD50 (μg/kg)b
Holotoxin (150kDa) 0.33 ± 0.03 NDc
Complex 1.1 ± 0.17 1.0 ± 0.15
Holotoxin in complexa 0.33 ± 0.05 0.29 ± 0.043
a

LD50 value of BoNT/B complex was normalized to holotoxin content. BoNT/B holotoxin constituted about 28.5% of total protein content.

b

Mean ± S.E.M, n ≥8.

c

ND: not determined