Table 2.
Parameters of cone ERG recordings
| Control cones | GCAPs−/− cones | |
|---|---|---|
| Io (photons μm−2) | 2180 ± 380 (13) | 918 ± 110 (13)* |
| Rmax (μV) | 13.5 ± 0.6 (13) | 16.2 ± 1.0 (13)* |
| Time-to-peak (ms) | 121 ± 4 (13) | 211 ± 5 (13)** |
| Integration time (ms) | 183 ± 28 (13) | 423 ± 21 (13)** |
| SFD (photons−1 μm2) | 3.7E-04 ± 6.5E-05 (13) | 1.0E-03 ± 1.4E-04 (13)** |
| IS (photons μm−2 s−1) | 12,900 ± 3100 (7) | 1100 ± 280 (7)* |
| IR (photons μm−2 s−1) | 94,300 ± 26,100 (7) | 3900 ± 770 (7)* |
| k, Hill coefficient | 0.47 ± 0.04 (7) | 0.70 ± 0.03 (7)** |
Mean ± SEM (n). Student's t test determined significant differences:
*p < 0.05,
**p < 0.005. IS is parameter of Weber–Fechner function in Figure 6C. IR and k are parameters obtained from the fit with Equation 2 in Figure 5C.