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. 2011 Jan 18;2(1):29–39. doi: 10.1007/s13300-010-0013-5
Liraglutide n =1363 Exenatide n =231 Placebo n =524
Cardiovascular risk markers, relative change (%)
Brain natriuretic peptide −11.9* −3.9 1.4
High-sensitivity C-reactive protein −23.1† −15.6* −3.0
Lipids, change (mg/dL)
Total cholesterol −2.3* −0.9 0.2
LDL-cholesterol −3.6† −2.7‡ −2.3‡
HDL-cholesterol −0.7† −0.9* −0.5‡
Triglycerides −3.6* −0.9 −0.4

*P<0.01 vs. baseline.

P<0.001 vs. baseline.

P<0.05 vs. baseline.

HDL=high-density lipoprotein; LDL=low-density lipoprotein.

Adapted with permission from: Plutzky J, Garber A, Falahati A, Taft AD, Paultzer NR. Reductions in lipids and CV risk markers in patients with type 2 diabetes treated with liraglutide: a meta-analysis. 20th World Diabetes Congress; October 18–22, 2009; Montreal, Canada. Abstract O-0542. Available at: http://www.diabetes.ca. Accessed August 15, 2009.