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. 2011 Mar 15;2(5):256–268. doi: 10.1021/cn100106a

Figure 9.

Figure 9

Estrogen and BT-SERM neuroprotection is attenuated by inhibition of PI3K/AkT and Src/ERK signaling and also by inhibition of GPCR by pertussis toxin or antagonism of GPR30 by G-15, whereas only estrogenic neuroprotection is inhibited by ER antagonist ICI.