Table 2.
Variable | BMDCs |
BMMs |
||||||
---|---|---|---|---|---|---|---|---|
WT |
p47phox-/- |
WT |
p47phox-/- |
|||||
gMFI | No. of cells | gMFI | No. of cells | gMFI | No. of cells | gMFI | No. of cells | |
MHC Class II | ||||||||
Medium | 72 | 5481 | 123 | 5749 | 230 | 3195 | 342 | 3970 |
Pn | 123 | 4630 | 100 | 6976 | 1241 | 6377 | 1877 | 6590 |
Lm | 141 | 4568 | 210 | 6466 | 958 | 7242 | 895 | 7418 |
Control | 56 | 6521 | 60 | 7119 | 366 | 4140 | 343 | 7518 |
CD80 | ||||||||
Medium | 503 | 4550 | 1033 | 6477 | 462 | 4955 | 384 | 5017 |
Pn | 621 | 5900 | 1147 | 6383 | 558 | 5824 | 721 | 7163 |
Lm | 511 | 6059 | 1656 | 5743 | 451 | 6550 | 582 | 7501 |
Control | 130 | 6461 | 127 | 7843 | 324 | 8207 | 290 | 7375 |
CD86 | ||||||||
Medium | 336 | 5590 | 266 | 6848 | 278 | 44,879 | 351 | 4280 |
Pn | 751 | 6129 | 309 | 7344 | 439 | 4969 | 529 | 7198 |
Lm | 427 | 4438 | 1035 | 5859 | 677 | 7490 | 725 | 7516 |
Control | 114 | 5807 | 86 | 8522 | 245 | 4140 | 232 | 7375 |
CD40 | ||||||||
Medium | 208 | 5764 | 130 | 6673 | 821 | 3586 | 446 | 4513 |
Pn | 379 | 6122 | 255 | 7494 | 2142 | 6699 | 2028 | 7040 |
Lm | 355 | 4435 | 755 | 6069 | 2592 | 7353 | 1374 | 6979 |
Control | 114 | 5807 | 127 | 7843 | 73 | 7375 | 75 | 7375 |
APCs from WT and p47phox-/- mice were cultured with 1 108 CFUs/mL of UVi Pn or Lm for 24 hours in vitro.
gMFI, geometric mean fluorescence intensity.