Figure 3.
Effects of flavonoids on BACE-1 activity in a cell free assay. ANOVA reveals a significant main effect of the treatment groups across the doses tested (P<0.001). Post-hoc comparisons show statistical significant BACE-1 activity inhibition across the doses tested for baicalein (P<0.001), apigenin (P<0.02), luteolin (P<0.02), quercetin (P<0.001) and kaempferol (P<0.001) but no significant effect of α-naphthoflavone, β-naphthoflavone, genistein, daidzein, taxifolin, PD98059 and aminogenitein on BACE-1 activity (P>0.05).