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. Author manuscript; available in PMC: 2012 Jun 17.
Published in final edited form as: Biochem Biophys Res Commun. 2011 May 23;409(4):814–819. doi: 10.1016/j.bbrc.2011.05.096

Fig. 3.

Fig. 3

In vitro inhibition of SerRS. In (A), total calf liver tRNA (3 µg) was aminoacylated with 3H-serine as described in Materials and Methods with various concentrations of SB-217452. In (B), naturally-occurring, purified tRNA[Ser]Sec, purified calf liver tRNASer and tRNA[Ser]Sec, and tRNASer transcripts (0.075 A260 unit) were aminoacylated with 3H-serine in the presence or absence of 20 µM SB-217452. Results shown are counts per minute (CPM) of 3H-serine.