Table 3.
Comparison of genotype and allele frequencies between patients with mesial temporal lobe epilepsy with (CoA+) and without (CoA-) corpora amylacea in the hippocampus
| Group | Genotype frequency (%) | Allele frequency (%) | ||||
|---|---|---|---|---|---|---|
| Ex-76 T/A | ||||||
| TT | TA | AA | T | A | ||
| CoA+ | 6 (30) | 14 (70) | 0 | 26 (65) | 14 (35) | |
| CoA | 15 (68.18) | 7 (31.82) | 0 | 37 (84.09) | 7 (15.91) | |
| P-value | 0.016* | 0.04 | ||||
| G2677T | ||||||
| GG | GT | TT | G | T | ||
| CoA+ | 6 (25.00) | 15 (62.50) | 3 (12.50) | 27 (56.25) | 21 (43.75) | |
| CoA | 1 (4.55) | 11 (50.00) | 10 (45.45) | 13 (29.55) | 31 (70.45) | |
| P-value | 0.02 | 0.01 | ||||
| C3435T | ||||||
| CC | CT | TT | C | T | ||
| CoA+ | 0 | 11 (45.83) | 13 (54.17) | 11 (22.92) | 37 (77.08) | |
| CoA | 0 | 7 (31.82) | 15 (68.18) | 7 (15.91) | 37 (84.09) | |
| P-value | 0.33 | 0.4 | ||||
| C1236T | ||||||
| CC | CT | TT | C | T | ||
| CoA+ | 2 (8.33) | 10 (41.67) | 12 (50.00) | 14 (29.17) | 34 (70.83) | |
| CoA | 3 (13.64) | 5 (22.73) | 14 (63.64) | 11 (25) | 33 (75) | |
| P-value | 0.38 | 0.65 | ||||
| +139C/T | ||||||
| CC | CT | TT | C | T | ||
| CoA+ | 4 (16.67) | 18 (75.00) | 2 (8.33) | 26 (54.17) | 22 (45.83) | |
| CoA | 1 (4.55) | 12 (54.55) | 9 (40.91) | 14 (31.82) | 30 (68.18) | |
| P-value | 0.06 | 0.03 | ||||
*
Significant in logistic regression analysis. Odd’s ratio (OR) = 5, 95% confidence intervals (CI) = 1.34–18.55