TABLE 3.

Cost Estimates of Alternative Snhl Evaluation Approaches Based on Diagnostic Yields

Testing yields	Bilateral			Unilateral	Overall
	Mild to moderate	Moderately severe	Severe to profound
GJB2 screen (N = 161)	15.5% (N = 45)	5.0% (N = 20)	37.7% (N = 71)	0.0% (N = 25)	18.0%
Imaging (N = 616)	21.2% (N = 144)	24.7% (N = 81)	29.9% (N = 241)	35.7% (N = 150)	27.3%
Laboratory test	0.0%	0.0%	0.3%	0.0%	0.07%
Cost estimates (per 100 children)
Simultaneous evaluation	$193,200	$193,200	$193,200	$193,200	$193,200
GJB2 paradigm	$141,096	$152,005	$121,530	n/a	$139,020
Imaging paradigm	$145,900	$144,034	$144,763	$103,00	$145,766

Reprinted from Otolaryngology – Head and Neck Surgery, Vol. 131, num. 6, Diego A. Preciado, Lynne H.Y. Lim, Aliza P. Cohen, Colm Madden, David Myer, Chris Ngo, John K. Bradshaw, Louise Lawson, Daniel I. Choo and John H. Greinwald Jr, “A diagnostic paradigm for childhood idiopathic sensorineural hearing loss,” pp. 804–809, at p. 809, Copyright 2004 American Academy of Otolaryngology – Head and Neck Surgery Foundation, Inc., with permission from Elsevier.