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. 2011 Mar 21;91(2):340–349. doi: 10.1093/cvr/cvr079

Figure 1.

Figure 1

Schematic diagram depicting the experimental protocols. (A) Effects of HG, IPC, and hyperosmolarity (HOsm) on infarct size in WT mice subjected to coronary occlusion followed by reperfusion; (B) effects of overexpression of the GTP cyclohydrolase (GTPCH) 1 gene on I/R injury with or without IPC in the presence or absence of HG or l-NAME; (C) effects of GTPCH-1 overexpression on IPC-induced changes in the mitochondrial permeability transition pore (mPTP) in the presence or absence of HG and/or l-NAME.