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. 2010 Nov 15;91(3):363–378. doi: 10.1038/labinvest.2010.187

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Copyright © 2011 United States and Canadian Academy of Pathology, Inc.

This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Representative histological analysis of lung tissues derived from an adenocarcinoma patient: HE staining (a, b, d) and immunofluorescence staining for pro-SP-C and CD90 (c, e). Images in (b, c) and (d, e) are shown from mirror sections, respectively. (a) A lower magnification of lung adenocarcinoma. (b, c) Higher magnifications from (a). Well-differentiated adenocarcinoma in (b) showed expression of pro-SP-C (green) and CD90 (red) in (c). (d, e) Higher magnifications from (b, c). Cancer cells that showed severe atypical nuclei and clear nucleoli in (d) expressed both pro-SP-C and CD90 in (e, arrowheads). Scale bars: (a–c) 400 μm (d, e) 50 μm.