Table 2.
Frequency of NKT cells in the skin and the blood of patients with CHS
| Frequency of NKT in skin1 (%) |
Frequency of NKT in blood2 (%) | ||||
|---|---|---|---|---|---|
| UPN | Allergen | NACDG score/duration (h) | Vα24 | Vβ11 | Vα24 |
| CD2 | Paraphenylene diamine | 2+/48 | 1.72 | 1.50 | <0.1 |
| CD4 | Epoxy resin | 1+/48 | 5.50 | 5.00 | <0.1 |
| CD6 | NiSO4 | 2+/96 | 3.50 | 4.20 | <0.1 |
| CD8 | Diazolidinyl urea | 2+/96 | 5.80 | 7.00 | <0.1 |
| CD9 | Epoxy resin | 2+/48 | 33.00 | 29.00 | <0.1 |
| CD10 | Neomycin | 2+/48 | 4.50 | 6.50 | <0.1 |
| Average frequency in skin lesions (±SD) | 9.00±8.86 | 11.803±10.05 | |||
NACDG, North American contact dermatitis group; UPN, unique patient number.
1
Frequency of double-positive cells=(frequency of Vα24/CD2 or Vβ11/CD2 double-positive cells/total no. of CD2 single-positive cells)×100.
2
Estimation by two-color flow cytometry of NKT cells (Vα24/CD2 double-positive lymphocytes) in peripheral blood.
3
P=0.36, not statistically significant on unpaired t-test.